Sadik A. Khuder, D.D.S., M.P.H., P.h.D.
Professor of Medicine, Statistics, and Public Health
College of Medicine and Life Sciences
The University of Toledo
3120 Glendale Ave
Toledo, Ohio 43614
Phone: (419) 383-4089
EDUCATION
- B.D.S. General Dentistry, University of Baghdad, 1977
- M.P.H. Epidemiology, University of Alabama at Birmingham, 1982
- Ph.D. Biostatistics, University of Alabama in Birmingham, 1992
EMPLOYMENT
- 1989-1990 Statistical analyst, Dept. of Biostatistics and Dept. of Medicine, Univ. of Alabama at Birmingham
- 1990-1992 Biostatistician, Dept. of Medicine, University of Alabama at Birmingham
- 1992-1993 Biostatistician, Cancer Center & Instructor, Dept. of Preventive Medicine and Community Health, University of Texas Medical Branch
- 1994-1998 Assistant Professor, Dept. of Medicine, Medical College of Ohio.
- 1997-1998 Assistant Professor, Dept. of Public Health, Medical College of Ohio
- 1998-2003 Associate Professor, Dept. of Medicine and Dept. of Public Health, Medical College of Ohio
- 2004-present Professor, Dept. of Medicine & School of Population Health, University of Toledo.
- 2005-present Senior biostatistician, Jacobson Center for Clinical and Translational Research, University of Toledo Health Science Campus
- 2014-present Professor, Department of Mathematics & Statistics, College of Natural Sciences, and Mathematics, University of Toledo.
HONORS
- Richard Anderson Research Award / Southern Regional Council on Statistics 1992.
- International Association for the Study of Lung Cancer / Grant for invited paper in the 9th World Conference on Lung Cancer - Japan, September 2000.
- Dean’s Award for Advising Excellence 2019.
TEACHING
1. SCHEDULED GRADUATE TEACHING
A. Current Teaching Assignment in the MPH program
PUBH 611 Categorical Data Analysis
Course Coordinator and 100% teaching effort
Fall semester – 2004-present
Number of students 10-15
PUBH 613 Molecular Epidemiology
Course Coordinator and 100% teaching effort
Fall semester – 2005-present
Number of students 25-45
PUBH 615 Clinical Epidemiology
Course Coordinator and 100% teaching effort
Spring semester – 2004-2007, 100% DL course (2008-present)
Number of students 30-45
PUBH 606 Advanced Biostatistics
Course Coordinator and 100% teaching effort
Spring semester – 1998-present
Number of students 45-60
PUBH 603 Advanced Epidemiology
Course Coordinator and 100% teaching effort
Summer semester – 1998-present
Number of students 45-60
PUBH 679 Independent Study in Biostatistics
Every semester – 1996-present
Number of students 1-2 per semester
B. Current Teaching Assignment in the Bioinformatics program
BIPG 520 Statistical Methods in Bioinformatics
Course Coordinator and 100% teaching effort
Fall semester – 2003-present
Number of students 10-15
BIPG 550 Microarray Analysis
Course Coordinator and 100% teaching effort
Summer semester (1 hour credit) – 2009-present
Number of students 5-10
BIPG Advanced Programming in Bioinformatics
Course Coordinator and 60% teaching effort
Fall semester – 2021
Number of students 2
BIPG6400 Application of Bioinformatics
Five lectures and labs for 30% teaching effort
Spring semester – 2003-present
Number of students 10-15
BRIM6200 Biomarker Discovery, Validation & Implementation
One lecture and lab for 5% teaching effort
Spring semester – 2009-present
Number of students 10-15
C. Current Teaching Assignment in the MSBS/PhD program
BSMP 532/732 Statistical Methods I
Course Coordinator and 100% teaching effort
Spring semester – 2001-present
Number of students 20-30
BMSP6390 Mentored Research
Course Coordinator and 100% teaching effort
Fall / Spring semester – 2018-present
Number of students 1-4
D. Current Teaching Assignment for Medical Students
Longitudinal Thread - Research First year medical student
Four lecture for 15% teaching effort
Fall semester – 2017-present
Number of students 170
Reproductive System Second year medical student
One lecture for 5% teaching effort
Fall semester – 2018-present
Number of students 150
Cardiovascular System Second year medical student
One lecture for 5% teaching effort
Fall semester – 2019-present
Number of students 150
USMLE Step I Review of Biostatistics Second year medical student
Spring semester – 2018
E. Past Teaching Assignment
- PUBH 600 Public Health Statistics 1996-2004
- PUBH 601 Public Health Epidemiology 1996-2003
- MEDI 532 Introductory Biostatistics 1995-2001
- MEDI 605 Advanced Biostatistics 1995-2000
- OCCH 602 Research Methods 1996-1997
MENTORING FOR THESIS RESEARCH: MSOH & INDUSTRIAL HYGIENE
- Tammy Arthur, “Prevalence of infectious diseases and associated symptoms in wastewater treatment employees”,December 1997
- Zachary Krabill, “The incidence of work-related injuries and illnesses in Ohio hospitals : a comparative study of the workers' compensation claims from 1993 to 1996”, December 1997
- Dan Helman, “Worker exposure to airborne chromium and its association with reported clinical symptomology”, December 1997
- Linda King, “Reported occupational exposure to HIV : incidence and application of recent recommendations for post-exposure chemoprophylaxis (immune deficiency)”, June 1998
- Michele Franketi, “Assessment of complete blood count variations associated with low-level benzene exposure”, June 1998
- Steven Kinn, “The effectiveness of safety and health education/training within the plumbing and pipefitting industry of northwestern Ohio”, June 2000
- Robert Koedam, “A comparison of the injuries and illnesses experienced by employees in the metal fabrication and nursing home industry in Philadelphia”, December 2001
- Meenakshi Kaw, “Meta-analysis of agricultural risk factors for non-Hodgkin's lymphoma 1”, December 2001
- Mahdi Jahangir-Blourchian, “Meta-analysis of agricultural risk factors for non-Hodgkin's lymphoma 2”, December 2001
- Arif Peshmam, “Environmental risk factors for autoimmune diseases“, December 2003
MENTORING FOR THESIS RESEARCH: BIOINFORMATIC PROGRAM
- Eric Haynes, “Identifying common genes from rheumatoid arthrisis, systemic lupus, multiple sclerosis and Sjögren's Syndrome by pooling existing microarray data”, June 2013
- Nicole Carr, “Data pooling to identify differentially expressed genes in lung cancer of nonsmokers”, June 2016.
- Oluwatobi Lasisi, “Potential genetic biomarkers for Sjogren’s syndrome”, December 2019.
- Prabhjot Kaur, “Combining transcriptomic data for COPD”, December 2019.
- Ammar Eljack, “Potential genetic biomarkers for cardiomyopathy”, June 2020.
- Joyeeta Dutta, “Identifying a biomarker for Systemic Sclerosis using existing genomic data”,June 2021.
- Bhuwan Rai, “Data Pooling to Investigate the Abundance of Gut Microbiome Composition in Autoimmune Disease”, June 2021.
- Alexander McCartney, “'Using Existing Omics Data to Identify Multiple Sclerosis Biomarkers', June 2021.
DISSERTATION COMMITTEE
- Dan Cipriani. Application of the Rasch Measurement Model to examine the utility of medical diagnostic tests. Applied Measurement and Statistics (Christine Fox, Chair), 2005
- Suoto Akpanudo. Clinical Psychologists and Smoking Cessation: Treatment Practices and Perceptions. Health Education (James Price, Chair), June 2006
- D’Anna Mullins, Transcriptional regulation of antioxidant and DNA repair transcript abundance in human bronchial epithelial cells Biomedical Sciences (James Willey , Chair), June 2007
- Marlyne Wood. Parental/guardian predictors of well controlled and poorly controlled asthmatic African American youths.Health Education (James Price, Chair), June 2007
- Joyce Balls. African American primary care physicians’ perceptions and practices regarding smoking cessation therapy.Health Education (James Price, Chair), June 2009
- Michael Valigosky. Infection control perceptions and practices of spiritual care providers: An application of the protection motivation theory. Health Education (Debra Boardley, Chair), June 2009
- Sam Shepard. The characterization and utilization of middle-range sequence patterns within the human genome.Bioinformatics (Alexei Fedorov, Chair), June 2010
- Ashwin Prakash. Evolution and function of compositional patterns in mammalian genomes. Bioinformatics (Alexei Fedorov, Chair), June 2011
- Jennifer Wohlwend. An examination of emergency contraception use by undergraduate college students in the Midwest using the integrated behavioral model. Health Education (Tavis Glassman, Chair), June 2012
- April Ames. Application of Geographic Information Systems to investigate the association of health symptoms near biosolid applied fields. Geography (Kevin Czajkowski, chair) June 2014
- Shuhao Qiu. Computational simulation and analysis of uutations: nucleotide fixation, allelic age and rare genetic variations in population. Bioinformatics (Alexei Fedorov, Chair), June 2015
- Ying Nie. Positional Mapping for Blood Pressure Loci on Rat Chromosome 9.Cardiovascular and Metabolic Diseases (Bina Joe, Chair), June 2015
- Xiaolu Zhang. Cis-acting genetic variants that alter ERCC5 regulation as a prototype to characterize cisregulation of key protective genes in normal bronchial epithelial cells. (James C. Willey, Chair), June 2017
- Rajib Dutta. 1000 human genomes carry widespread signatures of GC biased gene conversion. Bioinformatics (Alexei Fedorov, Chair), June 2017.
- Dulat Bekbolsynov. Medical Microbiology and Immunology. A new concept of immunogenicity to calculate the risk Stratification for kidney transplantation. Medical Microbiology & Immunology (Stanislaw Stepkowski, Chair), June 2017.
- Daniel Craig. Low Frequency Airway Epithelial Cell Mutation Pattern Associated with Lung Cancer Risk. Cancer Biology (James Willey, Chair), June 2019.
- Ahmed Al-Khudhair. Anti PD-1/PD-L1 Immunotherapy, New Era in the Fight Against Cancer, Genomic and Transcriptomic Exploration. Molecular Medicine (Juan Jaume, Chair), December 2019.
- Zakaria Alyousif. Passive Leg Movement and NO-Mediated Vascular Function: The Impact of Obstructive Sleep Apnea (OSA). Exercise and Rehabilitation Sciences (Barry Scheuermann, Chair), June 2020.
- Priti Singh. Using Rauch model. Applied Measurement and Statistics (Noela Haughton, Chair), June 2020.
- Katsumi Takeno. Within- and Between-Day Reliability of Corticomotor Excitability Assessment Techniques in the Upper Extremity: A Reliability Study. Exercise and Rehabilitation Sciences (Grant Norte, Chair), June 2020.
- Nilgun Sezginis. Factors Associated with Breast Cancer Screening Behaviors among the United States Born Versus Foreign Born Middle Eastern Women: A Mixed Methods Approach. Health Education (Shipra Singh, Chair), December 2020.
- Lijun Liu, Measurement (Noela Haughton, Chair), June 2021.
- Monica William. Analyzing the impact of Social Network Strength of Ties on Diabetes Self-Care Management in Older Adults. Health Education (Victoria Steiner, Chair), June 2021.
- Rajesh Nagisetty, Geography and planning (Bhuiyam Alam, Chair), expected June 2022.
- Khaled Alganem. Network-based multi-omics integration of chip-based kinase activity arrays with transcriptional and proteomic cellular signatures. Neuroscience (Robert McCullumsmith, Chair), expected June 2022.
- Abdul-rizaq Hamoud. Examining differential cancer rates in severe mental illness. Neuroscience (Robert McCullumsmith, Chair), expected June 2023.
THESIS COMMITTEE MSOH & INDUSTRIAL HYGIENE
- Page Miller. Measurements of organic vapor emissions from petroleum wastewater treatment vents. (Michael Bisesi, Chair), June 1997
- Ralph Caringi. Measurement of airborne volatile organic vapors collected at an oil refinery wastewater treatment operation. (Michael Bisesi, Chair), June 1997
- David Breitigam. Particle size distribution analysis on various processes in a beryllia ceramics plant. (Farhang Akbar, Chair), June 1997
- Denny Bitovski. Occupational and non-occupational exposure to extremely low frequency magnetic fields of school employees in a Canadian school district. (Farhang Akbar, Chair), June 1997
- James Swanson. Evaluation of airborne carbon monoxide gas levels in residential settings and comparison to reported levels in ambient and occupational settings. (Michael Bisesi, Chair), June 1997
- Gina Rejent. An evaluation of work related incident trends for a hazardous waste cleanup company. (Farhang Akbar, Chair), June 1997
- Barbara Kessler Cotton. Analysis of Arsenic-in Flyash Exposure Derived from Archived Database in Coal Burning Facilities. (Farhang Akbar, Chair), June 1997
- Monty Stollar. Comparison of air sampling results for total, inhalable, and respirable particulates at a pulp and paper mill. (Michael Bisesi, Chair), June 1997
- Kent Huang. Postural stability and balance of individuals using respirators (Farhang Akbar, Chair), June 1997
- Paul Kriwinsky. Stress levels in MRI and CT technicians. (Farhang Akbar, Chair), June 1997
- Maureen Sullivan. Comparison of colorimetric and atomic absorption spectrometric analyses for detection of lead in paint. (Michael Bisesi, Chair), June 1997
- Frank Petrik. Occupational exposure evaluation of explosive aerosols and vapors and bioaerosols during soil excavation and screening and composting of nitroaromatic and nitroamine contaminated soils. (Michael Bisesi, Chair), June 1997
- Owen Wagner. Relationship between OSHA safety and health program assessment (Form 33) and the number of violations. (Farhang Akbar, Chair), June 1998
- Gerald Schutt. Exposure of Tube Mill Operators to Extremely Low Frequency Magnetic Fields and Radiofrequency Electromagnetic Fields (Farhang Akbar, Chair), June 1998
- David Cronk. Airborne levels of respirable and non-respirable gram-negative bacteria and total bacteria associated with specific phases of municipal wastewater treatment. (Michael Bisesi, Chair), June 1998
- Edgar Pulido. Feasibility of respirators and goggles use to control formaldehyde exposure in gross anatomy laboratories. (Farhang Akbar, Chair), June 1998
- Michael Lampl. A perception survey to determine the effectiveness of an ergonomics injury management (EIM) process.(Sandra Woolley, Chair), June 1999
- Michael Groh. The industrial hygienists guide to performing effective limited indoor air quality investigations with biological implications. (Michael Bisesi, Chair), June 1999
- Barbara Wenzinger. An analysis of the level of lead fume and lead dust present in the lead fabrication area in medical radiation therapy departments. (Michael Bisesi, Chair), June 1999
- Yin Tan. Ventilation efficiency in a selected group of restaurants. (Farhang Akbar, Chair), June 2000
- Cynthia Twining. Bioaerosol levels of gram-negative bacteria at specific locations within phases of municipal waste water treatment. (Michael Bisesi, Chair), June 2000
- Karen McGhee. Comprehensive sampling of total aerobic and anaerobic bacteria at a waste water treatment. (Michael Bisesi, Chair), June 2000
- Brigitte Frank. Bioaerosol levels of fungi at specific locations within phases of municipal waste water treatment. (Michael Bisesi, Chair), June 2000
- Duan Deboo. Data Analysis Related to Some Indicators of Tobacco Smoke in Restaurants with Designated Smoking and Non-smoking Sections. (Farhang Akbar, Chair), June 2000
- Randall Brillhart. Silica dust exposure during concrete grinding in the construction industry. (Farhang Akbar, Chair), June 2000
- Rick Scott. StreamKeeper : a two-year investigation of potential biological pollution in the Swan Creek watershed of Northwest Ohio. (Michael Bisesi, Chair), June 2000
- Michael Gregory. Trends and causes of occupational fatalities in the United States from 1992 through 1999 : a review (Farhang Akbar, Chair), June 2001
- Sam Windom. Controlling environmental tobacco smoke by designating smoking rooms in nursing homes. (Farhang Akbar, Chair), June 2002
- Pet Bollenbacher. Surface sampling for fungi in the metalworking fluid environment. (Brian Harrington , Chair), June 2002
- Sonia Rosenberger. Biosafety education and training for human, animal, and plant pathogens. (Michael Bisesi, Chair), June 2004
- Ken Smigielski. Design and set up of a system for testing HEPA filter efficiency. (Farhang Akbar, Chair), June 2007
- Bess Weaver. Solar ultraviolet radiation exposure in outdoor work environment at Bowling Green, Ohio. (Farhang Akbar, Chair), June 2008
- Eugene Smith. Skid loader noise exposure assessment in a confinement dairy barn. (Sheryl Milz, Chair), June 2010
THESIS COMMITTEE MSBS
- Steven Haller. Marinobufagenin induced uremic cardiomyopathy: the role of passive immunization, rapamycin, and CD40 signaling in the generation of renal fibrosis. (Christopher Cooper, Chair), June 2005
- Andrew McSweeny. Identification of candidate genes within blood pressure QTL containing regions using gene expression data. (George Cicila, Chair), June 2008
- Malebari, Afnan Sami S. Improving a Method for High-Resolution HLA-Typing In Transplantation. (Stanislaw Stepkowski, Chair), June 2017.
THESIS COMMITTEE Bioinformatics
- Jason Bechtel. Characterization of genomic midrange inhomogeneity. (Alexei Fedorov, Chair), June 2008
- Theodor Rais. Conserved signals of non coding RNA across a set of 73 genes associated with autistic spectrum disorders. (Alexei Fedorov, Chair), June 2009
- Andrew McSweeny. Genome evolution model (GEM). (Alexei Fedorov, Chair), June 2010
- Maryam Nabiyouni. Mega-scale bioinformatics investigation of codon bias in vertebrates. (Alexei Fedorov, Chair), June 2011
- Arnab Saha Mandal. Computational analysis of the evolution of non-coding genomic sequences. (Alexei Fedorov, Chair), June 2014.
- Ahmad Alkhudhair. Inter-and-Intra-Populated Genetic Variations in Humans (Alexei Fedorov, Chair). December 2014.
- Diego A. Morales. A Bioinformatical Approach to COPD (James Willey, Chair), December 2016.
- Joseph S. Mainsah. Determnation of EarlyHuman Intercontinental Migration fromGenomic IBD Segments Flow Analysis (Alexei Fedorov, Chair), December 2016.
- Yuriy R. Yatskiv. Haplotype Analysis of an Archaic Denisovan Genome.(Alexei Fedorov, Chair), December 2016.
- Sharmistha Chakrabortty. SNPs and Indels Analysis in Human Genome using Computer Simulation and Sequencing Data. (Alexei Fedorov, Chair), June 2017
- Subhanwita Ghosh. (Alexei Fedorov, Chair), June 2017
- Patrick J Brennan. An Investigation of Personal Ancestry Using Haplotypes. (Alexei Fedorov, Chair), June 2017.
- Cole J. White. (Heather Conti, Chair), June 2018.
- Melisa Curtis. The effects of developmental pesticide exposure in mouse brain using integrative multi-omics". (James Burkett, Chair), December 2020.
- John Dillon (Heather Conti, Chair), December 2020.
THESIS COMMITTEE Pharmacy
- Tessa Hasting. Examining the impact of hybrid pharmacy practice model on medication adherence in patients with metabolic syndrome. Pharmacy (Robert Bechtol, Chair), June 2015.
- Duy Vu Le. Inflammatory bowel disease : cost-driving factors and the impact of different levels of cost sharing on health resource utilization (Varun Vaidya, Chair), May 2016.
- Janvi Sah. Factors and Outcomes Associated with 90-Days’ Supply of Prescription Medications (Varun Vaidya, Chair), May 2017.
- May F Alskaabi. Cost-Effectiveness of oral agents in Relapsing-Remitting Multiple Sclerosis Compared to Interferon-Based Therapy in Saudi Arabia. (Varun Vaidya, Chair), May 2017.
- Monika Salkar. Gender Disparity in Childhood Immunizations in India. (Varun Vaidya, Chair), May 2017.
- Angela Simon. Factors that Influence the Intent of Pharmacists in the Provision of Medication Therapy Management Services. (Sharrel Pinto, Chair), May 2018.
Articles Published in Peer-reviewed Journals
Khuder SA, Mutgi AB. Meta analysis of multiple myeloma and farming. Am J Ind Med 1997 Nov;32(5):510-6. PMID: 9327075
Khuder SA, Arthur T, Bisesi MS, Schaub EA. Prevalence of infectious diseases and associated symptoms in wastewater treatment workers. Am J Ind Med 1998 Jun;33(6):571-577. PMID:9582949
Khuder SA, Schaub E, Keller-Byrne J. Meta-analyses of Non-Hodgkin's lymphoma and farming. Scand J Work Environ Health 1998 Aug; 24:255-61. PMID:9754856
Khuder SA, Mutgi AB, Schaub E. Meta-analyses of brain cancer and farming. Am J Ind Med 1998 Sep;34:252-60. PMID:9698994
Khuder SA, Dayal HH, Mutgi AB, Willey JC, Dayal G. Effect of cigarette smoking on major histological types of lung cancer. Lung Cancer 1998 Oct; 22:15-21. PMID:9869103
Khuder SA, Schaub EA, Bisesi MS, Krabill ZT. Injuries and illness among hospital workers in Ohio: a study of workers’ compensation claims from 1993 to 1996. J Occup Environ Med 1999 Jan; 41:53-59. PMID:9924721
Khuder SA. Etiological clues to lip cancer from epidemiologic studies on farmers. Scand J Work Environ Health 1999 Apr; 25:125-130. PMID:10360467
Khuder SA, Youngdale MC, Bisesi MS, Schaub EA. Assessment of complete blood count variations among workers exposed to low levels of benzene. J Occup Environ Med 1999 Sep; 41:821-826. PMID:10491799
Khuder SA, Dayal HH, Mutgi AB. Age at smoking onset and its effect on smoking cessation. Addict Behav 1999 Sep-Oct; 24:673-677. PMID:10574304
Khuder SA, Mutgi AB, Schaub E, Tano BD. Meta-analyses of Hodgkin's disease among farmers. Scand J Work Environ Health 1999 Oct; 25:436-441. PMID:10569464
Khuder SA, Simon VJ Jr. Is there an association between passive smoking and breast cancer? Eur J Epidemiol 2000;16:1117-21. PMID:11484800
Khuder SA. Effect of cigarette smoking on major histological types of lung cancer: a meta-analysis. Lung Cancer 2001 Feb-Mar; 31:139-148. PMID:11165392
Khuder SA, Mutgi AB. Breast cancer and NSAID use: a meta-analysis. Br J Cancer 2001 May 4; 84 (9):1188-1192. PMID:11336469
Khuder SA, Mutgi AB, Nugent S. Smoking and breast cancer: a meta-analysis. Rev Environ Health. 2001 Jul-Sep; 16(4):253-261. PMID:12041881
Khuder SA, Mutgi AB. Effect of smoking cessation on major histological types of lung cancer. Chest 2001 Nov;120:1577-83. PMID:11713137
Khuder SA, Herial NA, Mutgi AB, Federman DJ. Nonsteroidal antiinflammatory drug use and lung cancer: ametaanalysis. Chest. 2005 Mar; 127:748-54. PMID:15764753
Khuder SA, Milz S, Jordan T, Price J, Silvestri K, . The impact of a smoking ban on hospital admissions for coronary heart disease. Prev Med. 2007 Jul;45(1):3-8. PMID:17482249
Khuder S, Milz S, Bisesi M, Vincent R, McNulty W, Czajkowski K. Health Survey ofResidents Living Near Biosolids Permitted Farm Fields. Arch Environ Occup Health. 2007 Jan-Feb; 62(1): 5-11. PMID:18171641
Khuder SA, Price JH, Jordan T, Khuder SS, Silvestri K. Cigarette smoking among adolescents in Northwest Ohio: correlates of prevalence and age at onset. Int J Environ Res Public Health. 2008 Dec;5(4):278-89. PMID:19190357
Khuder SA, Foos M, Herial NA, Mutgi AB, Khuder BS, Jung R. Urban/rural differences in hospital admissions with multiple sclerosis in selected counties in Ohio 1999-2004. The Open Epidemiology Journal. 2009, 2, 51-54.
Khuder SA, Al-Hashimi I, Mutgi AB, Altorok N. Identification of potential genomic biomarkers for Rheumatol Int 2015 May; 35(5):829-36. PMID: 25327574.
Khuder SA, Akpunonu B. Characteristics and Impact of Covid-19 Pandemic: A Word of Caution for Dental Practices. The Open Dentistry Journal, Volume 14, 2020.