Student Learning Objectives (SLO's) MSBS Degree
Graduating students WILL BE ABLE TO:
1)听听听听 Describe mammalian and nonmammalian genome structure and function, including (for example):听
a) Coding/non-coding sequence distribution
b)听Isochore structure
c)听Repeated element distribution
d)听Intron/exon structure and distribution
e)听Distribution and dynamics of methylation
f)听Transcription factor binding sites (for long- and short-range factors)
2)听听听 Discuss the processes of genome evolution, including (for example):听
a) Mechanisms of mutation
b) Consequences and exploitation of SNPs
c)听Fixation of mutations
d)听Genetic drift
别)听笔丑测濒辞驳别苍别迟颈肠蝉
f)听Major theories for the origin of novel genes
g)听Nature and basis of codon bias
3)听听听 Describe and use analytic tools associated with systems/bioinformatic approaches, including (for example):听
a) Transcriptomics 鈥� microarray analysis vs. deep sequencing
b) Proteomic mass spectroscopic methods (identification and abundance)
c)听Determining statistical significance in large bioinformatic datasets
d)听Determination and structure of interaction networks
e)听Functional network maps听
4)听听听 Carry out appropriate statistical analysis of sequence information, including (for example):听
a) Probabilistic methods
b)听Deterministic methods
c)听Machine learning methods, including Support Vector Machines (SVMs)
d)听Cluster analysis
5)听听听 Demonstrate competent use of existing bioinformatic and statistical software, including (for example):听
a) R statistical tools
b)听Alignments and their interpretation
c)听Phylogenetic analyses
d)听Programs to predict genes and transcription factor binding sites
e)听Programs to display, predict and analyze 3D biomolecule structures
6)听听听 Develop and use basic PERL programs for bioinformatic analyses, including (for example):听
a) Familiarity with the UNIX operating system
b)听Writing scripts for extracting information from databases
c)听Creating databases
d)听Interfacing with supercomputers
7)听听听 Apply bioinformatic methods to clinical problems, by demonstrating understanding of:听
a) Biomarker discovery and validation
b)听Major diseases such as cancer, diabetes, and autoimmunity
8)听听听 Communicate competently both in writing and orally听
a) With fellow team members in research projects
b)听With the broader scientific public
9)听听听 Demonstrate familiarity with and adherence to research ethics.